| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KIC58611.1 | KIC59723.1 | RM53_08075 | RM53_04740 | 3-hydroxy-3-methylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.754 |
| KIC58611.1 | KIC61070.1 | RM53_08075 | RM53_00370 | 3-hydroxy-3-methylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the transamination of D-amino acids and their alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.658 |
| KIC58611.1 | hisI | RM53_08075 | RM53_02860 | 3-hydroxy-3-methylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazole glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | 0.526 |
| KIC58611.1 | ispDF | RM53_08075 | RM53_00350 | 3-hydroxy-3-methylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.499 |
| KIC59646.1 | KIC59723.1 | RM53_04275 | RM53_04740 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.754 |
| KIC59646.1 | KIC61070.1 | RM53_04275 | RM53_00370 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Catalyzes the transamination of D-amino acids and their alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.658 |
| KIC59646.1 | hisI | RM53_04275 | RM53_02860 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Imidazole glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | 0.526 |
| KIC59646.1 | ispDF | RM53_04275 | RM53_00350 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.499 |
| KIC59723.1 | KIC58611.1 | RM53_04740 | RM53_08075 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-hydroxy-3-methylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.754 |
| KIC59723.1 | KIC59646.1 | RM53_04740 | RM53_04275 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.754 |
| KIC59723.1 | KIC61070.1 | RM53_04740 | RM53_00370 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the transamination of D-amino acids and their alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.686 |
| KIC59723.1 | hisI | RM53_04740 | RM53_02860 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazole glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | 0.844 |
| KIC59723.1 | ispDF | RM53_04740 | RM53_00350 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.619 |
| KIC61067.1 | KIC61068.1 | RM53_00355 | RM53_00360 | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.835 |
| KIC61067.1 | KIC61069.1 | RM53_00355 | RM53_00365 | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.815 |
| KIC61067.1 | KIC61070.1 | RM53_00355 | RM53_00370 | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Catalyzes the transamination of D-amino acids and their alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.828 |
| KIC61067.1 | hflX | RM53_00355 | RM53_00380 | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | GTPase HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.604 |
| KIC61067.1 | hfq | RM53_00355 | RM53_00375 | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.658 |
| KIC61067.1 | ispDF | RM53_00355 | RM53_00350 | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.651 |
| KIC61068.1 | KIC61067.1 | RM53_00360 | RM53_00355 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.835 |