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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIC61105.1phosphoribosyl-ATP pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)    
Predicted Functional Partners:
KIC61126.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.702
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.673
KIC54104.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.641
KIC61075.1
D-alanyl-D-alanine carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.610
KIC60974.1
Aldo/keto reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.604
KIC59720.1
Peptidase aspartic; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.598
KIC55834.1
tipN; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.587
hisI
Imidazole glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family.
    
 0.569
KIC60848.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.532
Your Current Organism:
Brevundimonas nasdae
NCBI taxonomy Id: 172043
Other names: B. nasdae, Brevundimonas nasdae Li et al. 2004, DSM 14572, JCM 11415, strain W1-2B
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