| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KIC57593.1 | KIC58780.1 | RM53_09835 | RM53_06070 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.502 |
| KIC57593.1 | KIC60986.1 | RM53_09835 | RM53_00685 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Chromosomal replication initiator protein DnaA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DnaA family. | 0.992 |
| KIC57593.1 | dnaA | RM53_09835 | RM53_09840 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.992 |
| KIC57593.1 | recF | RM53_09835 | RM53_09830 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Recombinase RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.945 |
| KIC57593.1 | recO | RM53_09835 | RM53_05675 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.448 |
| KIC58780.1 | KIC57593.1 | RM53_06070 | RM53_09835 | DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.502 |
| KIC58780.1 | KIC60986.1 | RM53_06070 | RM53_00685 | DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Chromosomal replication initiator protein DnaA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DnaA family. | 0.844 |
| KIC58780.1 | dnaA | RM53_06070 | RM53_09840 | DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.980 |
| KIC58780.1 | recO | RM53_06070 | RM53_05675 | DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.415 |
| KIC59238.1 | KIC60986.1 | RM53_05745 | RM53_00685 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chromosomal replication initiator protein DnaA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DnaA family. | 0.600 |
| KIC59238.1 | rpmE | RM53_05745 | RM53_06320 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. | 0.719 |
| KIC59238.1 | rpmJ | RM53_05745 | RM53_06610 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L36; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL36 family. | 0.719 |
| KIC60986.1 | KIC57593.1 | RM53_00685 | RM53_09835 | Chromosomal replication initiator protein DnaA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DnaA family. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.992 |
| KIC60986.1 | KIC58780.1 | RM53_00685 | RM53_06070 | Chromosomal replication initiator protein DnaA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DnaA family. | DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.844 |
| KIC60986.1 | KIC59238.1 | RM53_00685 | RM53_05745 | Chromosomal replication initiator protein DnaA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DnaA family. | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.600 |
| KIC60986.1 | KIC60988.1 | RM53_00685 | RM53_00695 | Chromosomal replication initiator protein DnaA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DnaA family. | Exopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.675 |
| KIC60986.1 | dnaA | RM53_00685 | RM53_09840 | Chromosomal replication initiator protein DnaA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DnaA family. | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.643 |
| KIC60986.1 | ppk | RM53_00685 | RM53_00690 | Chromosomal replication initiator protein DnaA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DnaA family. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.696 |
| KIC60986.1 | recF | RM53_00685 | RM53_09830 | Chromosomal replication initiator protein DnaA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DnaA family. | Recombinase RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.734 |
| KIC60986.1 | recO | RM53_00685 | RM53_05675 | Chromosomal replication initiator protein DnaA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DnaA family. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.654 |
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