Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KIC60905.1Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (878 aa)    
Predicted Functional Partners:
KIC60904.1
Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.962
KIC57164.1
Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.817
KIC55982.1
ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.815
mutM
5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
  
 0.710
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
   
    0.619
KIC60906.1
Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.558
KIC60907.1
prolyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.
       0.558
KIC60903.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.536
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
   
    0.526
KIC60908.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.486
Your Current Organism:
Brevundimonas nasdae
NCBI taxonomy Id: 172043
Other names: B. nasdae, Brevundimonas nasdae Li et al. 2004, DSM 14572, JCM 11415, strain W1-2B
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.