Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KIC60398.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)    
Predicted Functional Partners:
KIC60396.1
XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   0.945
KIC60399.1
Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
       0.813
KIC61087.1
Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
  0.807
KIC60397.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
KIC60359.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.760
KIC58847.1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.734
KIC56667.1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.721
KIC58454.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.717
KIC56013.1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.703
KIC60849.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.691
Your Current Organism:
Brevundimonas nasdae
NCBI taxonomy Id: 172043
Other names: B. nasdae, Brevundimonas nasdae Li et al. 2004, DSM 14572, JCM 11415, strain W1-2B
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