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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIC60402.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)    
Predicted Functional Partners:
KIC60401.1
Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
 
     0.853
KIC60403.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.815
KIC60400.1
EF hand domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.737
KIC59019.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.679
KIC60398.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.578
KIC60399.1
Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
       0.557
KIC59666.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.535
KIC61018.1
Histidine phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.534
KIC59745.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.500
KIC60397.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.490
Your Current Organism:
Brevundimonas nasdae
NCBI taxonomy Id: 172043
Other names: B. nasdae, Brevundimonas nasdae Li et al. 2004, DSM 14572, JCM 11415, strain W1-2B
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