Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kuATP-dependent DNA ligase; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (288 aa)    
Predicted Functional Partners:
KIC60437.1
ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.980
KIC60439.1
RNA signal recognition particle 4.5S RNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.628
KIC60441.1
3-demethylubiquinone-9 3-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.526
KIC55982.1
ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.518
KIC59032.1
DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.505
KIC60440.1
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.501
KIC60442.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.501
KIC60443.1
Lactoylglutathione lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.501
KIC59054.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.430
KIC52848.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.418
Your Current Organism:
Brevundimonas nasdae
NCBI taxonomy Id: 172043
Other names: B. nasdae, Brevundimonas nasdae Li et al. 2004, DSM 14572, JCM 11415, strain W1-2B
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