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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIC60462.1Inosine-5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.881
KIC59842.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.875
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
  
 0.725
KIC56753.1
Inosine-5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.679
KIC56840.1
Phosphate kinase; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
  
  
 0.636
KIC60659.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.561
KIC59761.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.560
KIC60658.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.518
KIC60578.1
PAS fold family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.501
KIC59832.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.501
Your Current Organism:
Brevundimonas nasdae
NCBI taxonomy Id: 172043
Other names: B. nasdae, Brevundimonas nasdae Li et al. 2004, DSM 14572, JCM 11415, strain W1-2B
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