Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KIC60462.1Inosine-5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.760
KIC56753.1
Inosine-5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.679
KIC60659.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.561
KIC59842.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.504
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
   
 0.412
KIC56840.1
Phosphate kinase; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
  
  
 0.407
KIC60658.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.406
Your Current Organism:
Brevundimonas nasdae
NCBI taxonomy Id: 172043
Other names: B. nasdae, Brevundimonas nasdae Li et al. 2004, DSM 14572, JCM 11415, strain W1-2B
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