| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KIC56298.1 | KIC56765.1 | RM53_13400 | RM53_11605 | Nitrogen regulatory protein P-II 1; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.414 |
| KIC56298.1 | KIC59642.1 | RM53_13400 | RM53_04255 | Nitrogen regulatory protein P-II 1; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ammonia channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| KIC56298.1 | KIC59842.1 | RM53_13400 | RM53_04815 | Nitrogen regulatory protein P-II 1; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.631 |
| KIC56298.1 | nadE | RM53_13400 | RM53_08695 | Nitrogen regulatory protein P-II 1; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.555 |
| KIC56765.1 | KIC56298.1 | RM53_11605 | RM53_13400 | uroporphyrin-III methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Nitrogen regulatory protein P-II 1; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.414 |
| KIC56765.1 | KIC59642.1 | RM53_11605 | RM53_04255 | uroporphyrin-III methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Ammonia channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.438 |
| KIC56765.1 | KIC59648.1 | RM53_11605 | RM53_04285 | uroporphyrin-III methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Acetolactate synthase catalytic subunit; Catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.400 |
| KIC56765.1 | KIC59842.1 | RM53_11605 | RM53_04815 | uroporphyrin-III methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.448 |
| KIC56765.1 | leuB | RM53_11605 | RM53_04260 | uroporphyrin-III methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.406 |
| KIC56765.1 | nadE | RM53_11605 | RM53_08695 | uroporphyrin-III methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.449 |
| KIC57570.1 | KIC59642.1 | RM53_09680 | RM53_04255 | Response regulator receiver protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ammonia channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.513 |
| KIC57570.1 | KIC59761.1 | RM53_09680 | RM53_04990 | Response regulator receiver protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| KIC57570.1 | KIC59842.1 | RM53_09680 | RM53_04815 | Response regulator receiver protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.575 |
| KIC57570.1 | nadE | RM53_09680 | RM53_08695 | Response regulator receiver protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.584 |
| KIC59641.1 | KIC59642.1 | RM53_04250 | RM53_04255 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ammonia channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.610 |
| KIC59642.1 | KIC56298.1 | RM53_04255 | RM53_13400 | Ammonia channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nitrogen regulatory protein P-II 1; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| KIC59642.1 | KIC56765.1 | RM53_04255 | RM53_11605 | Ammonia channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.438 |
| KIC59642.1 | KIC57570.1 | RM53_04255 | RM53_09680 | Ammonia channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Response regulator receiver protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.513 |
| KIC59642.1 | KIC59641.1 | RM53_04255 | RM53_04250 | Ammonia channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.610 |
| KIC59642.1 | KIC59644.1 | RM53_04255 | RM53_04265 | Ammonia channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.436 |
STRING v12.5 is now available!
