Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KIC59710.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (567 aa)    
Predicted Functional Partners:
pleD
Response regulator PleD; Involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.944
KIC56013.1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
   0.872
KIC61087.1
Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
  0.813
KIC59705.1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.812
KIC57578.1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.798
KIC58847.1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   0.787
KIC56667.1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.777
KIC58454.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
0.759
KIC60578.1
PAS fold family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.748
KIC59703.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.743
Your Current Organism:
Brevundimonas nasdae
NCBI taxonomy Id: 172043
Other names: B. nasdae, Brevundimonas nasdae Li et al. 2004, DSM 14572, JCM 11415, strain W1-2B
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