Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KIC59761.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (523 aa)    
Predicted Functional Partners:
KIC60668.1
PAS fold family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.992
KIC58818.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.984
KIC60578.1
PAS fold family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.981
KIC59832.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.981
KIC58852.1
Signal peptide protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.980
KIC58454.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.977
KIC57871.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.970
pleD
Response regulator PleD; Involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.961
KIC60658.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
0.952
KIC58933.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
0.950
Your Current Organism:
Brevundimonas nasdae
NCBI taxonomy Id: 172043
Other names: B. nasdae, Brevundimonas nasdae Li et al. 2004, DSM 14572, JCM 11415, strain W1-2B
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