close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIC59823.1Blue light sensor protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)    
Predicted Functional Partners:
KIC59761.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.807
KIC60578.1
PAS fold family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.651
KIC59832.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.651
KIC58818.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.651
KIC58852.1
Signal peptide protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.651
KIC58454.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.580
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
   
    0.529
KIC60668.1
PAS fold family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.516
KIC61116.1
Response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.437
pleD
Response regulator PleD; Involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.437
Your Current Organism:
Brevundimonas nasdae
NCBI taxonomy Id: 172043
Other names: B. nasdae, Brevundimonas nasdae Li et al. 2004, DSM 14572, JCM 11415, strain W1-2B
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.