Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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[Homology]
Score
KIC57796.1Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)    
Predicted Functional Partners:
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 0.999
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
 
 0.992
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.937
KIC56916.1
Thiamine monophosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.895
KIC55794.1
Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.886
KIC56724.1
Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.882
KIC60809.1
Molybdopterin biosynthesis protein MoeB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.826
KIC57797.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.779
KIC57862.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.748
KIC57799.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
     
 0.653
Your Current Organism:
Brevundimonas nasdae
NCBI taxonomy Id: 172043
Other names: B. nasdae, Brevundimonas nasdae Li et al. 2004, DSM 14572, JCM 11415, strain W1-2B
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