close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIC57799.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (271 aa)    
Predicted Functional Partners:
KIC59214.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
KIC58226.1
Folylpolyglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family.
 
 0.996
KIC55783.1
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
 
 0.995
folE-2
GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.936
folE
GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.931
KIC58986.1
Class IV aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.899
KIC57800.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
KIC57801.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
KIC59723.1
Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.730
KIC60869.1
Chloroperoxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.680
Your Current Organism:
Brevundimonas nasdae
NCBI taxonomy Id: 172043
Other names: B. nasdae, Brevundimonas nasdae Li et al. 2004, DSM 14572, JCM 11415, strain W1-2B
Server load: medium (64%) [HD]