| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KIC56521.1 | ruvC | RM53_12045 | RM53_09350 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.432 |
| KIC57818.1 | KIC57819.1 | RM53_09355 | RM53_09360 | Magnesium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cation-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.632 |
| KIC57818.1 | ruvA | RM53_09355 | RM53_09345 | Magnesium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.628 |
| KIC57818.1 | ruvB | RM53_09355 | RM53_09340 | Magnesium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.438 |
| KIC57818.1 | ruvC | RM53_09355 | RM53_09350 | Magnesium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.637 |
| KIC57819.1 | KIC57818.1 | RM53_09360 | RM53_09355 | Cation-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Magnesium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.632 |
| KIC57819.1 | ruvA | RM53_09360 | RM53_09345 | Cation-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.465 |
| KIC57819.1 | ruvC | RM53_09360 | RM53_09350 | Cation-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.465 |
| KIC57864.1 | ruvA | RM53_09320 | RM53_09345 | acyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.526 |
| KIC57864.1 | ruvB | RM53_09320 | RM53_09340 | acyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.675 |
| KIC57864.1 | ruvC | RM53_09320 | RM53_09350 | acyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.525 |
| KIC59260.1 | polA | RM53_05875 | RM53_10580 | Single-stranded DNA exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.535 |
| KIC59260.1 | ruvC | RM53_05875 | RM53_09350 | Single-stranded DNA exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.454 |
| KIC59260.1 | topA | RM53_05875 | RM53_14040 | Single-stranded DNA exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.438 |
| def | ruvC | RM53_01675 | RM53_09350 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.570 |
| polA | KIC59260.1 | RM53_10580 | RM53_05875 | DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Single-stranded DNA exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.535 |
| polA | ruvA | RM53_10580 | RM53_09345 | DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.596 |
| polA | ruvB | RM53_10580 | RM53_09340 | DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.641 |
| polA | ruvC | RM53_10580 | RM53_09350 | DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.646 |
| polA | topA | RM53_10580 | RM53_14040 | DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.932 |
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