| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KIC59794.1 | KIC60806.1 | RM53_05220 | RM53_01605 | Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.423 |
| KIC59794.1 | KIC61057.1 | RM53_05220 | RM53_00275 | Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.604 |
| KIC59794.1 | clpB | RM53_05220 | RM53_09430 | Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase AAA; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.827 |
| KIC59794.1 | clpP | RM53_05220 | RM53_00130 | Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.423 |
| KIC59794.1 | dnaJ | RM53_05220 | RM53_10785 | Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.578 |
| KIC59794.1 | dnaK | RM53_05220 | RM53_10790 | Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.604 |
| KIC59794.1 | groEL | RM53_05220 | RM53_08060 | Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.585 |
| KIC59794.1 | grpE | RM53_05220 | RM53_00895 | Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.447 |
| KIC60806.1 | KIC59794.1 | RM53_01605 | RM53_05220 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.423 |
| KIC60806.1 | KIC61057.1 | RM53_01605 | RM53_00275 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.654 |
| KIC60806.1 | clpB | RM53_01605 | RM53_09430 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase AAA; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.960 |
| KIC60806.1 | clpS | RM53_01605 | RM53_13515 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | Clp protease ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.450 |
| KIC60806.1 | dnaK | RM53_01605 | RM53_10790 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.654 |
| KIC60806.1 | groEL | RM53_01605 | RM53_08060 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.586 |
| KIC60806.1 | grpE | RM53_01605 | RM53_00895 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.686 |
| KIC60963.1 | KIC61057.1 | RM53_01505 | RM53_00275 | Heat-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.578 |
| KIC60963.1 | clpB | RM53_01505 | RM53_09430 | Heat-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the small heat shock protein (HSP20) family. | ATPase AAA; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.797 |
| KIC60963.1 | dnaJ | RM53_01505 | RM53_10785 | Heat-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.526 |
| KIC60963.1 | dnaK | RM53_01505 | RM53_10790 | Heat-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.647 |
| KIC60963.1 | grpE | RM53_01505 | RM53_00895 | Heat-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the small heat shock protein (HSP20) family. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.622 |
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