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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIC57576.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (678 aa)    
Predicted Functional Partners:
KIC59761.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
0.997
KIC58454.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.996
KIC58852.1
Signal peptide protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.994
KIC60578.1
PAS fold family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.991
KIC59832.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.991
KIC58818.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.990
KIC57570.1
Response regulator receiver protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.989
KIC57871.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.987
KIC55174.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.986
pleD
Response regulator PleD; Involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; Derived by automated computational analysis using gene prediction method: Protein Homology.
0.984
Your Current Organism:
Brevundimonas nasdae
NCBI taxonomy Id: 172043
Other names: B. nasdae, Brevundimonas nasdae Li et al. 2004, DSM 14572, JCM 11415, strain W1-2B
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.