| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KIC56765.1 | KIC57153.1 | RM53_11605 | RM53_09990 | uroporphyrin-III methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.645 |
| KIC56765.1 | KIC59842.1 | RM53_11605 | RM53_04815 | uroporphyrin-III methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.448 |
| KIC57153.1 | KIC56765.1 | RM53_09990 | RM53_11605 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.645 |
| KIC57153.1 | KIC57154.1 | RM53_09990 | RM53_09995 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.636 |
| KIC57153.1 | KIC57155.1 | RM53_09990 | RM53_10000 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endoribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.505 |
| KIC57153.1 | KIC59842.1 | RM53_09990 | RM53_04815 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.527 |
| KIC57153.1 | KIC60707.1 | RM53_09990 | RM53_00960 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Integrase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.514 |
| KIC57153.1 | dadA | RM53_09990 | RM53_09985 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Amino acid dehydrogenase; Oxidative deamination of D-amino acids. | 0.531 |
| KIC57153.1 | lysK | RM53_09990 | RM53_10005 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | lysine--tRNA ligase; Class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.414 |
| KIC57154.1 | KIC57153.1 | RM53_09995 | RM53_09990 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.636 |
| KIC57154.1 | KIC57155.1 | RM53_09995 | RM53_10000 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endoribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.588 |
| KIC57154.1 | dadA | RM53_09995 | RM53_09985 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Amino acid dehydrogenase; Oxidative deamination of D-amino acids. | 0.445 |
| KIC57154.1 | lysK | RM53_09995 | RM53_10005 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | lysine--tRNA ligase; Class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.491 |
| KIC57155.1 | KIC57153.1 | RM53_10000 | RM53_09990 | Endoribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.505 |
| KIC57155.1 | KIC57154.1 | RM53_10000 | RM53_09995 | Endoribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.588 |
| KIC57155.1 | dadA | RM53_10000 | RM53_09985 | Endoribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Amino acid dehydrogenase; Oxidative deamination of D-amino acids. | 0.504 |
| KIC57155.1 | lysK | RM53_10000 | RM53_10005 | Endoribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | lysine--tRNA ligase; Class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.636 |
| KIC59842.1 | KIC56765.1 | RM53_04815 | RM53_11605 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.448 |
| KIC59842.1 | KIC57153.1 | RM53_04815 | RM53_09990 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.527 |
| KIC59842.1 | KIC60707.1 | RM53_04815 | RM53_00960 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Integrase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.940 |