Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KIC57189.1Diguanylate phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (525 aa)    
Predicted Functional Partners:
KIC58842.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.894
KIC61034.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.849
KIC57191.1
Rod-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.697
KIC59761.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.666
pleD
Response regulator PleD; Involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 
 0.658
flgI
Flagellar basal body P-ring biosynthesis protein FlgA; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
  
    0.617
KIC57190.1
Flagellar basal-body protein FlbY; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.541
KIC59799.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
0.522
KIC60880.1
Type II secretion system protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.486
flgG
Makes up the distal portion of the flagellar basal body rod; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thick flagella; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.486
Your Current Organism:
Brevundimonas nasdae
NCBI taxonomy Id: 172043
Other names: B. nasdae, Brevundimonas nasdae Li et al. 2004, DSM 14572, JCM 11415, strain W1-2B
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