| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KIC55977.1 | mraY | RM53_14165 | RM53_11300 | UDP-phosphate glucose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.724 |
| KIC55977.1 | murA | RM53_14165 | RM53_12630 | UDP-phosphate glucose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.577 |
| KIC55977.1 | murJ | RM53_14165 | RM53_10820 | UDP-phosphate glucose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.532 |
| KIC56698.1 | mraY | RM53_11660 | RM53_11300 | Flagellar basal-body rod protein FlgF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the flagella basal body rod proteins family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.581 |
| KIC56698.1 | murJ | RM53_11660 | RM53_10820 | Flagellar basal-body rod protein FlgF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the flagella basal body rod proteins family. | Membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.581 |
| KIC56849.1 | glnD | RM53_10810 | RM53_10825 | Peroxiredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | protein-PII uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.433 |
| KIC56849.1 | murJ | RM53_10810 | RM53_10820 | Peroxiredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.498 |
| KIC56849.1 | trpS | RM53_10810 | RM53_10815 | Peroxiredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.773 |
| KIC56853.1 | glnD | RM53_10830 | RM53_10825 | GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology. | protein-PII uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.615 |
| KIC56853.1 | murJ | RM53_10830 | RM53_10820 | GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.528 |
| KIC56853.1 | trpS | RM53_10830 | RM53_10815 | GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.422 |
| KIC61053.1 | mraY | RM53_00255 | RM53_11300 | Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.506 |
| KIC61053.1 | mrdB | RM53_00255 | RM53_00260 | Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.997 |
| KIC61053.1 | murA | RM53_00255 | RM53_12630 | Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.586 |
| KIC61053.1 | murJ | RM53_00255 | RM53_10820 | Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.490 |
| glnD | KIC56849.1 | RM53_10825 | RM53_10810 | protein-PII uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | Peroxiredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.433 |
| glnD | KIC56853.1 | RM53_10825 | RM53_10830 | protein-PII uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.615 |
| glnD | murJ | RM53_10825 | RM53_10820 | protein-PII uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | Membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.763 |
| glnD | trpS | RM53_10825 | RM53_10815 | protein-PII uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.515 |
| mraY | KIC55977.1 | RM53_11300 | RM53_14165 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-phosphate glucose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.724 |