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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kynATryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (265 aa)    
Predicted Functional Partners:
KIC60650.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.920
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.898
KIC55782.1
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.870
KIC56870.1
Class V aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.646
KIC56535.1
Amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.620
KIC56557.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.568
KIC56536.1
Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.532
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
  
 0.529
KIC58210.1
Amine oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.487
KIC59091.1
Phenylalanine-4-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.479
Your Current Organism:
Brevundimonas nasdae
NCBI taxonomy Id: 172043
Other names: B. nasdae, Brevundimonas nasdae Li et al. 2004, DSM 14572, JCM 11415, strain W1-2B
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