Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KIC56370.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)    
Predicted Functional Partners:
KIC56369.1
3-ketoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.688
KIC56421.1
2-keto-3-deoxygluconate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.672
KIC56906.1
Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.531
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.517
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.441
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.424
KIC55748.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.424
KIC56368.1
Pectate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.404
KIC56422.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.404
KIC60453.1
TonB-dependent receptor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.401
Your Current Organism:
Brevundimonas nasdae
NCBI taxonomy Id: 172043
Other names: B. nasdae, Brevundimonas nasdae Li et al. 2004, DSM 14572, JCM 11415, strain W1-2B
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.