Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KIC56424.1Methionine sulfoxide reductase B; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)    
Predicted Functional Partners:
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.987
msrA-2
Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.985
KIC58656.1
Thio:disulfide interchange protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.750
KIC59226.1
Cytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.703
KIC56393.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.618
KIC56392.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.566
grpE
Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]
   
 
 0.491
KIC56884.1
Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.491
KIC56922.1
Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.486
KIC60781.1
Antioxidant AhpC; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.448
Your Current Organism:
Brevundimonas nasdae
NCBI taxonomy Id: 172043
Other names: B. nasdae, Brevundimonas nasdae Li et al. 2004, DSM 14572, JCM 11415, strain W1-2B
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