Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
KIC56409.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (266 aa)    
Predicted Functional Partners:
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.833
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.822
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.815
KIC60682.1
WD-40 repeat-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.808
KIC55834.1
tipN; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.808
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.805
KIC61057.1
Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.803
KIC59794.1
Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.792
KIC60400.1
EF hand domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.789
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
  0.789
Your Current Organism:
Brevundimonas nasdae
NCBI taxonomy Id: 172043
Other names: B. nasdae, Brevundimonas nasdae Li et al. 2004, DSM 14572, JCM 11415, strain W1-2B
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