| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KIC56540.1 | guaA | RM53_12165 | RM53_07045 | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.437 |
| KIC56540.1 | pyrG | RM53_12165 | RM53_13240 | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.957 |
| KIC56540.1 | rplE | RM53_12165 | RM53_15930 | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.999 |
| KIC56540.1 | rplF | RM53_12165 | RM53_15945 | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.999 |
| KIC56540.1 | rplM | RM53_12165 | RM53_05840 | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.999 |
| KIC56540.1 | rplR | RM53_12165 | RM53_15950 | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.999 |
| KIC56540.1 | rplW | RM53_12165 | RM53_15880 | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.999 |
| KIC56540.1 | rpmC | RM53_12165 | RM53_15910 | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L29; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL29 family. | 0.999 |
| KIC56540.1 | rpmD | RM53_12165 | RM53_15960 | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L30; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| guaA | KIC56540.1 | RM53_07045 | RM53_12165 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.437 |
| guaA | ndk | RM53_07045 | RM53_00730 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.584 |
| guaA | pyrG | RM53_07045 | RM53_13240 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.992 |
| guaA | rplE | RM53_07045 | RM53_15930 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.558 |
| guaA | rplM | RM53_07045 | RM53_05840 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.856 |
| guaA | rplR | RM53_07045 | RM53_15950 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.799 |
| guaA | rplW | RM53_07045 | RM53_15880 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.495 |
| guaA | rpmC | RM53_07045 | RM53_15910 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L29; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL29 family. | 0.493 |
| guaA | rpmD | RM53_07045 | RM53_15960 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L30; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.693 |
| ndk | guaA | RM53_00730 | RM53_07045 | Phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.584 |
| ndk | pyrG | RM53_00730 | RM53_13240 | Phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.960 |
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