Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KIC56278.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)    
Predicted Functional Partners:
KIC56801.1
Electron transfer flavoprotein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.898
KIC56802.1
Electron transfer flavoprotein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.886
KIC60958.1
Glutamine cyclotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.746
parE
DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
       0.623
KIC56280.1
Polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.623
KIC60618.1
Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.
 
   
 0.601
lldD
Lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
  
 
 0.596
KIC56225.1
NADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
   
 0.594
KIC56277.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0246 family.
       0.577
KIC56310.1
Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.574
Your Current Organism:
Brevundimonas nasdae
NCBI taxonomy Id: 172043
Other names: B. nasdae, Brevundimonas nasdae Li et al. 2004, DSM 14572, JCM 11415, strain W1-2B
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