| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KIC56298.1 | KIC59842.1 | RM53_13400 | RM53_04815 | Nitrogen regulatory protein P-II 1; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.607 |
| KIC56298.1 | glnA | RM53_13400 | RM53_13395 | Nitrogen regulatory protein P-II 1; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.930 |
| KIC56920.1 | KIC59733.1 | RM53_10925 | RM53_04810 | Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.912 |
| KIC56920.1 | KIC59842.1 | RM53_10925 | RM53_04815 | Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.937 |
| KIC56920.1 | KIC60707.1 | RM53_10925 | RM53_00960 | Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Integrase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.925 |
| KIC56920.1 | glnA | RM53_10925 | RM53_13395 | Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.923 |
| KIC56920.1 | purQ | RM53_10925 | RM53_03980 | Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.900 |
| KIC59733.1 | KIC56920.1 | RM53_04810 | RM53_10925 | Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.912 |
| KIC59733.1 | KIC59842.1 | RM53_04810 | RM53_04815 | Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| KIC59733.1 | KIC60707.1 | RM53_04810 | RM53_00960 | Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Integrase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.900 |
| KIC59733.1 | carA | RM53_04810 | RM53_04770 | Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbamoyl-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. | 0.905 |
| KIC59733.1 | carB | RM53_04810 | RM53_03870 | Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. | 0.913 |
| KIC59733.1 | glmS | RM53_04810 | RM53_00920 | Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.917 |
| KIC59733.1 | glnA | RM53_04810 | RM53_13395 | Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.942 |
| KIC59733.1 | purF | RM53_04810 | RM53_06100 | Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.906 |
| KIC59733.1 | purQ | RM53_04810 | RM53_03980 | Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.900 |
| KIC59842.1 | KIC56298.1 | RM53_04815 | RM53_13400 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nitrogen regulatory protein P-II 1; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.607 |
| KIC59842.1 | KIC56920.1 | RM53_04815 | RM53_10925 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.937 |
| KIC59842.1 | KIC59733.1 | RM53_04815 | RM53_04810 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| KIC59842.1 | KIC60707.1 | RM53_04815 | RM53_00960 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Integrase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.946 |
