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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIC55982.1ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (562 aa)    
Predicted Functional Partners:
KIC57593.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.992
KIC57164.1
Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.984
polA
DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.982
ligA
DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
     
 0.934
KIC56814.1
D,D-heptose 1,7-bisphosphate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the gmhB family.
  
 0.886
KIC61059.1
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.862
KIC60904.1
Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.826
KIC60905.1
Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.806
KIC60906.1
Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.783
KIC59010.1
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.748
Your Current Organism:
Brevundimonas nasdae
NCBI taxonomy Id: 172043
Other names: B. nasdae, Brevundimonas nasdae Li et al. 2004, DSM 14572, JCM 11415, strain W1-2B
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