| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KIC55945.1 | KIC60723.1 | RM53_13960 | RM53_01085 | DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.722 |
| KIC55945.1 | cmk | RM53_13960 | RM53_02665 | DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.452 |
| KIC55945.1 | coaD | RM53_13960 | RM53_07300 | DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.818 |
| KIC55945.1 | der | RM53_13960 | RM53_06115 | DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP-binding protein Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.554 |
| KIC55945.1 | ffh | RM53_13960 | RM53_08310 | DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA-binding protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belongs to t [...] | 0.466 |
| KIC55945.1 | ftsY | RM53_13960 | RM53_08705 | DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.560 |
| KIC55945.1 | pyrH | RM53_13960 | RM53_13110 | DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.430 |
| KIC55945.1 | rlmH | RM53_13960 | RM53_08285 | DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S rRNA methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.479 |
| KIC55945.1 | rnpA | RM53_13960 | RM53_10430 | DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.547 |
| KIC55945.1 | rsmI | RM53_13960 | RM53_11115 | DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 16S rRNA methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.422 |
| KIC60723.1 | KIC55945.1 | RM53_01085 | RM53_13960 | Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.722 |
| KIC60723.1 | rnpA | RM53_01085 | RM53_10430 | Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.960 |
| cmk | KIC55945.1 | RM53_02665 | RM53_13960 | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.452 |
| cmk | der | RM53_02665 | RM53_06115 | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP-binding protein Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.982 |
| cmk | ffh | RM53_02665 | RM53_08310 | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA-binding protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belongs to t [...] | 0.828 |
| cmk | ftsY | RM53_02665 | RM53_08705 | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.623 |
| cmk | pyrH | RM53_02665 | RM53_13110 | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.480 |
| coaD | KIC55945.1 | RM53_07300 | RM53_13960 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.818 |
| coaD | pyrH | RM53_07300 | RM53_13110 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.431 |
| der | KIC55945.1 | RM53_06115 | RM53_13960 | GTP-binding protein Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.554 |
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