STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B4V02_17640Unannotated protein. (335 aa)    
Predicted Functional Partners:
B4V02_21290
Unannotated protein.
  
 0.890
topA
Unannotated protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 0.890
B4V02_17650
Unannotated protein.
  
 0.869
polA
Unannotated protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.852
recA
Unannotated protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.835
B4V02_13650
Unannotated protein.
  
 
 
 0.794
B4V02_15445
Unannotated protein.
 
 
 0.774
B4V02_04945
Unannotated protein.
  
   
 0.763
mutL
Unannotated protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
  
 0.757
B4V02_04965
Unannotated protein.
 
    0.756
Your Current Organism:
Paenibacillus kribbensis
NCBI taxonomy Id: 172713
Other names: JCM 11465, KCTC 0766BP, P. kribbensis, Paenibacillus kribbensis Yoon et al. 2003, strain AM49
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.