Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SDB27464.1Exodeoxyribonuclease V alpha subunit. (706 aa)    
Predicted Functional Partners:
SDB27471.1
Hypothetical protein.
  
 
 0.808
SDB27474.1
Hypothetical protein.
       0.773
SDB34824.1
DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...]
  
 0.733
addA
DNA helicase/exodeoxyribonuclease V, subunit A; ATP-dependent DNA helicase.
  
 
 0.690
recD2
Exodeoxyribonuclease V alpha subunit; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.
  
  
 
0.656
SDB27461.1
HNH endonuclease.
       0.623
SDB27455.1
DNA polymerase-3 subunit alpha.
    
 0.589
SDB27482.1
Sigma-70 region 2; Belongs to the sigma-70 factor family.
       0.574
SDB27445.1
Single-strand DNA-binding protein.
   
 
 0.563
SDB27449.1
Hypothetical protein.
       0.545
Your Current Organism:
Eubacterium oxidoreducens
NCBI taxonomy Id: 1732
Other names: ATCC 43585, DSM 3217, E. oxidoreducens, Eubacterium oxidoreducans, strain G41
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