STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC115045658E3 ubiquitin-protein ligase Itchy-like. (894 aa)    
Predicted Functional Partners:
cflar
CASP8 and FADD like apoptosis regulator.
    
 0.991
traf6
TNF receptor associated factor 6.
    
 0.987
LOC115056053
NEDD4-like E3 ubiquitin-protein ligase WWP2.
   
  0.968
ENSENLP00000046272
WW domain containing E3 ubiquitin protein ligase 1.
   
  0.968
mdm2
MDM2 proto-oncogene.
    
 0.967
LOC115048350
Neurogenic locus notch homolog protein 1-like.
    
 0.963
LOC115051771
Neurogenic locus notch homolog protein 1-like.
    
 0.963
ENSENLP00000004347
Ubiquitin B.
    
 0.949
rps27a
Ribosomal protein S27a.
    
  0.942
LOC115051645
E3 ubiquitin-protein ligase NEDD4-like.
   
 0.942
Your Current Organism:
Echeneis naucrates
NCBI taxonomy Id: 173247
Other names: E. naucrates, live sharksucker
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.