Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
slf1SMC5-SMC6 complex localization factor 1. (906 aa)    
Predicted Functional Partners:
ENSENLP00000035431
RAD18 E3 ubiquitin protein ligase.
   
 
 0.990
ENSENLP00000047936
ATR serine/threonine kinase.
    
 0.976
ENSENLP00000053539
BRCA1 associated RING domain 1.
   
 0.967
nbn
Nibrin.
    
 0.963
rad1
RAD1 checkpoint DNA exonuclease.
    
 0.960
rad17
RAD17 checkpoint clamp loader component.
  
 0.960
ENSENLP00000005948
ATM serine/threonine kinase.
   
 0.959
cdc45
Cell division cycle 45.
   
 
 0.952
ENSENLP00000035331
Tumor protein p53 binding protein, 1.
    
 0.949
psmd12
Proteasome 26S subunit, non-ATPase 12.
    
 0.947
Your Current Organism:
Echeneis naucrates
NCBI taxonomy Id: 173247
Other names: E. naucrates, live sharksucker
Server load: low (16%) [HD]