Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
msh3mutS homolog 3. (1111 aa)    
Predicted Functional Partners:
msh2
mutS homolog 2.
  
0.999
mlh1
mutL homolog 1.
 
 0.998
msh6
mutS homolog 6.
   
 0.995
pcna
Proliferating cell nuclear antigen.
  
 0.994
ENSENLP00000045272
PMS1 homolog 2, mismatch repair system component.
 
 0.993
pms1
PMS1 homolog 1, mismatch repair system component.
 
 0.992
snx8
Sorting nexin 8.
    
   0.974
ENSENLP00000006877
Exonuclease 1.
  
 0.957
mlh3
mutL homolog 3.
  
 0.937
rad51
RAD51 recombinase.
  
 0.932
Your Current Organism:
Echeneis naucrates
NCBI taxonomy Id: 173247
Other names: E. naucrates, live sharksucker
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.