Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSENLP00000012295SMAD family member 6a. (501 aa)    
Predicted Functional Partners:
ENSENLP00000010369
SMAD specific E3 ubiquitin protein ligase 1.
    
 0.976
LOC115047311
E3 ubiquitin-protein ligase SMURF2.
    
 0.976
LOC115044607
E3 ubiquitin-protein ligase SMURF2-like.
    
 0.976
LOC115050019
Mothers against decapentaplegic homolog 5.
    
0.973
ENSENLP00000013012
SMAD family member 1.
    
0.973
smad9
SMAD family member 9.
    
0.973
smad3
SMAD family member 3.
    
0.972
LOC115040841
Mothers against decapentaplegic homolog 3.
    
0.972
smad2
SMAD family member 2.
    
0.972
LOC115048648
Mothers against decapentaplegic homolog 2.
    
0.972
Your Current Organism:
Echeneis naucrates
NCBI taxonomy Id: 173247
Other names: E. naucrates, live sharksucker
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