STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
agap3ArfGAP with GTPase domain, ankyrin repeat and PH domain 3. (1344 aa)    
Predicted Functional Partners:
arfgap1
ADP ribosylation factor GTPase activating protein 1.
     
0.717
unc5b
Unc-5 netrin receptor B.
    
  0.696
LOC115035784
arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1-like.
   
0.694
tanc1
Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1.
    
  0.661
ENSENLP00000022626
Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4).
    
  0.613
LOC115050107
Cyclin-dependent kinase 4 inhibitor D-like.
    
  0.613
rapgef2
Rap guanine nucleotide exchange factor 2.
   
  0.605
appl1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
   
  0.594
appl2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
   
  0.594
pcna
Proliferating cell nuclear antigen.
    
  0.579
Your Current Organism:
Echeneis naucrates
NCBI taxonomy Id: 173247
Other names: E. naucrates, live sharksucker
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.