ALM11529.1 protein (Peribacter riflensis) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Score

ALM11529.1

seryl-tRNA synthetase. (441 aa)

Predicted Functional Partners:

ALM11528.1

0.741

cysS

0.692

argS

0.669

ALM11527.1

0.669

ALM10836.1

0.650

trpS

0.649

ALM11530.1

0.634

hisS

0.623

ALM10759.1

0.619

pheT

0.615

Your Current Organism:

Peribacter riflensis

NCBI taxonomy Id: 1735162
Other names: C. Peribacter riflensis, Candidatus Peregrinibacteria bacterium RIFOXYA2_FULL_PER-ii_58_14, Candidatus Peregrinibacteria bacterium RIFOXYB2_FULL_PER-ii_58_17, Candidatus Peregrinibacteria bacterium RIFOXYC2_FULL_PER-ii_58_32, Candidatus Peregrinibacteria bacterium RIFOXYD1_FULL_PER-ii_59_16, Candidatus Peregrinibacteria bacterium RIFOXYD2_FULL_PER-ii_51_23, Candidatus Peribacter riflensis, Candidatus Peribacteria bacterium RIFOXYA2_FULL_PER-ii_58_14, Candidatus Peribacteria bacterium RIFOXYB2_FULL_PER-ii_58_17, Candidatus Peribacteria bacterium RIFOXYC2_FULL_PER-ii_58_32, Candidatus Peribacteria bacterium RIFOXYD1_FULL_PER-ii_59_16, Candidatus Peribacteria bacterium RIFOXYD2_FULL_PER-ii_51_23

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALM10759.1	ALM10836.1	PeribacterB2_0265	PeribacterB2_0343	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	CMP/dCMP deaminase zinc-binding protein.	0.679
ALM10759.1	ALM11529.1	PeribacterB2_0265	PeribacterB2_1072	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	seryl-tRNA synthetase.	0.619
ALM10759.1	hisS	PeribacterB2_0265	PeribacterB2_0286	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	histidyl-tRNA synthetase.	0.586
ALM10759.1	trpS	PeribacterB2_0265	PeribacterB2_0684	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.	0.440
ALM10836.1	ALM10759.1	PeribacterB2_0343	PeribacterB2_0265	CMP/dCMP deaminase zinc-binding protein.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.679
ALM10836.1	ALM11529.1	PeribacterB2_0343	PeribacterB2_1072	CMP/dCMP deaminase zinc-binding protein.	seryl-tRNA synthetase.	0.650
ALM10836.1	pheT	PeribacterB2_0343	PeribacterB2_0925	CMP/dCMP deaminase zinc-binding protein.	Phenylalanyl-tRNA synthetase subunit beta; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.	0.623
ALM11527.1	ALM11528.1	PeribacterB2_1070	PeribacterB2_1071	Hypothetical protein.	Hypothetical protein.	0.697
ALM11527.1	ALM11529.1	PeribacterB2_1070	PeribacterB2_1072	Hypothetical protein.	seryl-tRNA synthetase.	0.669
ALM11527.1	ALM11530.1	PeribacterB2_1070	PeribacterB2_1073	Hypothetical protein.	Hypothetical protein.	0.552
ALM11528.1	ALM11527.1	PeribacterB2_1071	PeribacterB2_1070	Hypothetical protein.	Hypothetical protein.	0.697
ALM11528.1	ALM11529.1	PeribacterB2_1071	PeribacterB2_1072	Hypothetical protein.	seryl-tRNA synthetase.	0.741
ALM11528.1	ALM11530.1	PeribacterB2_1071	PeribacterB2_1073	Hypothetical protein.	Hypothetical protein.	0.609
ALM11529.1	ALM10759.1	PeribacterB2_1072	PeribacterB2_0265	seryl-tRNA synthetase.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.619
ALM11529.1	ALM10836.1	PeribacterB2_1072	PeribacterB2_0343	seryl-tRNA synthetase.	CMP/dCMP deaminase zinc-binding protein.	0.650
ALM11529.1	ALM11527.1	PeribacterB2_1072	PeribacterB2_1070	seryl-tRNA synthetase.	Hypothetical protein.	0.669
ALM11529.1	ALM11528.1	PeribacterB2_1072	PeribacterB2_1071	seryl-tRNA synthetase.	Hypothetical protein.	0.741
ALM11529.1	ALM11530.1	PeribacterB2_1072	PeribacterB2_1073	seryl-tRNA synthetase.	Hypothetical protein.	0.634
ALM11529.1	argS	PeribacterB2_1072	PeribacterB2_0623	seryl-tRNA synthetase.	arginyl-tRNA synthetase.	0.669
ALM11529.1	cysS	PeribacterB2_1072	PeribacterB2_1126	seryl-tRNA synthetase.	cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.692

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

50

average node degree:

9.09

avg. local clustering coefficient:

0.949

expected number of edges:

12

PPI enrichment p-value:

1.11e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051123

RNA polymerase II preinitiation complex assembly

8 of 18

2.92

9.32

1.35e-18

GO:0006367

Transcription initiation from RNA polymerase II promoter

9 of 34

2.7

9.28

2.13e-19

GO:0006352

DNA-templated transcription, initiation

10 of 81

2.36

8.24

2.13e-19

GO:0042789

mRNA transcription by RNA polymerase II

8 of 41

2.56

7.65

2.33e-16

GO:0060261

Positive regulation of transcription initiation from RNA polymerase II promoter

8 of 46

2.51

7.42

4.48e-16

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016251

RNA polymerase II general transcription initiation factor activity

5 of 25

2.57

4.39

3.55e-09

GO:0140296

General transcription initiation factor binding

5 of 54

2.24

3.54

6.18e-08

GO:0017025

TBP-class protein binding

4 of 28

2.43

3.15

8.77e-07

GO:0046982

Protein heterodimerization activity

8 of 334

1.65

2.94

2.81e-09

GO:0008134

Transcription factor binding

8 of 636

1.37

1.99

8.87e-08

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005669

Transcription factor TFIID complex

10 of 29

2.81

11.72

3.14e-24

GO:0033276

Transcription factor TFTC complex

6 of 14

2.9

7.14

3.19e-14

GO:0070461

SAGA-type complex

7 of 37

2.55

6.95

8.57e-15

GO:0000124

SAGA complex

4 of 23

2.51

3.73

6.89e-08

GO:0071339

MLL1 complex

4 of 34

2.34

3.35

2.61e-07

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4168

RNA polymerase II preinitiation complex assembly

9 of 10

3.23

12.24

1.25e-23

CL:4125

Transcription factor TFIID complex, and Transcription factor TFIIH holo complex

10 of 34

2.74

11.2

1.63e-23

CL:4172

SLIK (SAGA-like) complex, and Lateral mesoderm formation

5 of 5

3.27

6.35

2.44e-12

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

ccan03022

Basal transcription factors

9 of 34

2.7

9.97

5.56e-21

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-76042

RNA Polymerase II Transcription Initiation And Promoter Clearance

9 of 49

2.54

8.68

5.40e-19

MAP-75953

RNA Polymerase II Transcription Initiation

9 of 49

2.54

8.68

5.40e-19

MAP-73779

RNA Polymerase II Transcription Pre-Initiation And Promoter Opening

9 of 49

2.54

8.68

5.40e-19

MAP-73776

RNA Polymerase II Promoter Escape

9 of 49

2.54

8.68

5.40e-19

MAP-674695

RNA Polymerase II Pre-transcription Events

9 of 101

2.22

6.9

4.69e-17

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0016591

RNA polymerase II, holoenzyme

10 of 64

2.47

9.27

4.03e-21

GOCC:0070461

SAGA-type complex

7 of 34

2.59

7.03

7.63e-15

GOCC:0071339

MLL1 complex

4 of 26

2.46

3.55

1.37e-07

GOCC:0005654

Nucleoplasm

11 of 696

1.47

3.04

1.99e-14

GOCC:1990234

Transferase complex

11 of 858

1.38

2.6

1.71e-13

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0396

Initiation factor

4 of 59

2.1

2.46

1.07e-05

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