| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACH52_0002 | ACH52_1000 | ACH52_0002 | ACH52_1000 | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | DNA polymerase III alpha subunit DnaE. | 0.990 |
| ACH52_0002 | ACH52_1868 | ACH52_0002 | ACH52_1868 | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | Helicase SNF2 family. | 0.952 |
| ACH52_0002 | ACH52_2815 | ACH52_0002 | ACH52_2815 | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | DNA polymerase III delta subunit HolA. | 0.992 |
| ACH52_0002 | ACH52_3876 | ACH52_0002 | ACH52_3876 | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | DNA polymerase III delta' subunit HolB. | 0.982 |
| ACH52_0002 | dnaA | ACH52_0002 | ACH52_0001 | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.996 |
| ACH52_0002 | dnaX | ACH52_0002 | ACH52_3246 | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | DNA polymerase III subunit gamma and tau DnaX; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.987 |
| ACH52_0002 | mutL | ACH52_0002 | ACH52_1395 | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.962 |
| ACH52_0002 | mutS | ACH52_0002 | ACH52_1393 | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.963 |
| ACH52_0002 | polA | ACH52_0002 | ACH52_3124 | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.996 |
| ACH52_0002 | polC | ACH52_0002 | ACH52_2413 | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | DNA polymerase III alpha subunit Gram positive type PolC; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.952 |
| ACH52_1000 | ACH52_0002 | ACH52_1000 | ACH52_0002 | DNA polymerase III alpha subunit DnaE. | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | 0.990 |
| ACH52_1000 | ACH52_2815 | ACH52_1000 | ACH52_2815 | DNA polymerase III alpha subunit DnaE. | DNA polymerase III delta subunit HolA. | 0.990 |
| ACH52_1000 | ACH52_3876 | ACH52_1000 | ACH52_3876 | DNA polymerase III alpha subunit DnaE. | DNA polymerase III delta' subunit HolB. | 0.986 |
| ACH52_1000 | dnaX | ACH52_1000 | ACH52_3246 | DNA polymerase III alpha subunit DnaE. | DNA polymerase III subunit gamma and tau DnaX; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.987 |
| ACH52_1000 | polA | ACH52_1000 | ACH52_3124 | DNA polymerase III alpha subunit DnaE. | DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.775 |
| ACH52_1000 | polC | ACH52_1000 | ACH52_2413 | DNA polymerase III alpha subunit DnaE. | DNA polymerase III alpha subunit Gram positive type PolC; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.918 |
| ACH52_1868 | ACH52_0002 | ACH52_1868 | ACH52_0002 | Helicase SNF2 family. | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | 0.952 |
| ACH52_1868 | polA | ACH52_1868 | ACH52_3124 | Helicase SNF2 family. | DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.977 |
| ACH52_2815 | ACH52_0002 | ACH52_2815 | ACH52_0002 | DNA polymerase III delta subunit HolA. | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | 0.992 |
| ACH52_2815 | ACH52_1000 | ACH52_2815 | ACH52_1000 | DNA polymerase III delta subunit HolA. | DNA polymerase III alpha subunit DnaE. | 0.990 |
