Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACH52_0359Radical SAM/B12-binding domain-containing protein. (499 aa)    
Predicted Functional Partners:
ACH52_0360
Radical SAM/B12-binding domain-containing protein.
 
  
 
0.978
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase CobT; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
    
  0.968
ACH52_0361
SAM-dependent methyltransferase.
 
     0.928
cobT-2
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase CobT; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
     
  0.900
ACH52_0358
Alpha/beta hydrolase.
       0.489
ACH52_2990
NAD/NADP octopine/nopaline dehydrogenase family protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
 
     0.475
ACH52_2570
Hypothetical protein.
 
     0.470
ACH52_3297
Hypothetical protein.
 
     0.465
bzaB
ThiC-like protein; Together with BzaA, catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Is thus involved in the anaerobic biosynthesis of dimethylbenzimidazole (DMB), the lower axial ligand of vitamin B12 (cobalamin). Requires BzaA for catalytic activity, as BzaB alone displays no activity. Belongs to the ThiC family. 5-hydroxybenzimidazole synthase subfamily.
       0.461
ACH52_0011
Hypothetical protein.
  
     0.459
Your Current Organism:
Eubacterium limosum
NCBI taxonomy Id: 1736
Other names: ATCC 8486, Bacteroides limosus, Butyribacterium limosum, Butyribacterium rettgeri, CCUG 16793, CIP 104169, DSM 20543, E. limosum, JCM 6421, JCM 9978, Mycobacterium limosum
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