STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACH52_0360Radical SAM/B12-binding domain-containing protein. (441 aa)    
Predicted Functional Partners:
ACH52_0359
Radical SAM/B12-binding domain-containing protein.
 
  
 
0.979
ACH52_0361
SAM-dependent methyltransferase.
 
  
  0.969
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase CobT; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
       0.757
bzaB
ThiC-like protein; Together with BzaA, catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Is thus involved in the anaerobic biosynthesis of dimethylbenzimidazole (DMB), the lower axial ligand of vitamin B12 (cobalamin). Requires BzaA for catalytic activity, as BzaB alone displays no activity. Belongs to the ThiC family. 5-hydroxybenzimidazole synthase subfamily.
       0.497
ACH52_2451
polyphosphate:AMP phosphotransferase Pap.
   
    0.491
bzaA
ThiC-like protein; Together with BzaB, catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Is thus involved in the anaerobic biosynthesis of dimethylbenzimidazole (DMB), the lower axial ligand of vitamin B12 (cobalamin). Requires BzaB for catalytic activity, as BzaA alone displays no activity. Belongs to the ThiC family. 5-hydroxybenzimidazole synthase subfamily.
       0.485
ACH52_0358
Alpha/beta hydrolase.
       0.454
ACH52_2990
NAD/NADP octopine/nopaline dehydrogenase family protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
 
     0.452
ACH52_1510
Cell division protein FtsI.
 
     0.411
Your Current Organism:
Eubacterium limosum
NCBI taxonomy Id: 1736
Other names: ATCC 8486, Bacteroides limosus, Butyribacterium limosum, Butyribacterium rettgeri, CCUG 16793, CIP 104169, DSM 20543, E. limosum, JCM 6421, JCM 9978, Mycobacterium limosum
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