| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACH52_0018 | ACH52_0370 | ACH52_0018 | ACH52_0370 | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.901 |
| ACH52_0018 | ACH52_2790 | ACH52_0018 | ACH52_2790 | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | 5'-nucleotidase/metallophosphoesterase domain-containing protein; Belongs to the 5'-nucleotidase family. | 0.916 |
| ACH52_0018 | cmk | ACH52_0018 | ACH52_1532 | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | Cytidylate kinase Cmk. | 0.924 |
| ACH52_0018 | pyrF | ACH52_0018 | ACH52_0409 | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | Orotidine 5'-phosphate decarboxylase PyrF; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.900 |
| ACH52_0018 | pyrH | ACH52_0018 | ACH52_1545 | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | UMP kinase PyrH; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.900 |
| ACH52_0018 | thyX | ACH52_0018 | ACH52_1093 | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | FAD-dependent thymidylate synthase ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.900 |
| ACH52_0018 | tmk | ACH52_0018 | ACH52_3878 | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | Thymidylate kinase Tmk; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.903 |
| ACH52_0018 | upp | ACH52_0018 | ACH52_1346 | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | Uracil phosphoribosyltransferase Upp; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.900 |
| ACH52_0370 | ACH52_0018 | ACH52_0370 | ACH52_0018 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | 0.901 |
| ACH52_0370 | ACH52_2790 | ACH52_0370 | ACH52_2790 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 5'-nucleotidase/metallophosphoesterase domain-containing protein; Belongs to the 5'-nucleotidase family. | 0.905 |
| ACH52_0370 | ACH52_2937 | ACH52_0370 | ACH52_2937 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Anaerobic ribonucleoside-triphosphate reductase NrdD. | 0.903 |
| ACH52_0370 | cmk | ACH52_0370 | ACH52_1532 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Cytidylate kinase Cmk. | 0.906 |
| ACH52_0370 | pyrF | ACH52_0370 | ACH52_0409 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Orotidine 5'-phosphate decarboxylase PyrF; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.900 |
| ACH52_0370 | pyrG | ACH52_0370 | ACH52_0460 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | CTP synthase PyrG; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.907 |
| ACH52_0370 | pyrH | ACH52_0370 | ACH52_1545 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | UMP kinase PyrH; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.900 |
| ACH52_0370 | thyX | ACH52_0370 | ACH52_1093 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | FAD-dependent thymidylate synthase ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.900 |
| ACH52_0370 | tmk | ACH52_0370 | ACH52_3878 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Thymidylate kinase Tmk; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.908 |
| ACH52_0370 | upp | ACH52_0370 | ACH52_1346 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Uracil phosphoribosyltransferase Upp; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.900 |
| ACH52_2790 | ACH52_0018 | ACH52_2790 | ACH52_0018 | 5'-nucleotidase/metallophosphoesterase domain-containing protein; Belongs to the 5'-nucleotidase family. | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | 0.916 |
| ACH52_2790 | ACH52_0370 | ACH52_2790 | ACH52_0370 | 5'-nucleotidase/metallophosphoesterase domain-containing protein; Belongs to the 5'-nucleotidase family. | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.905 |