| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACH52_0408 | ACH52_0410 | ACH52_0408 | ACH52_0410 | Dihydroorotase multifunctional complex type PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Dihydroorotate dehydrogenase electron transfer subunit. | 0.997 |
| ACH52_0408 | ACH52_1884 | ACH52_0408 | ACH52_1884 | Dihydroorotase multifunctional complex type PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Sulfite reductase subunit B AsrB. | 0.771 |
| ACH52_0408 | ACH52_2235 | ACH52_0408 | ACH52_2235 | Dihydroorotase multifunctional complex type PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Sulfite reductase subunit B AsrB. | 0.771 |
| ACH52_0408 | carA | ACH52_0408 | ACH52_0648 | Dihydroorotase multifunctional complex type PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Carbamoyl-phosphate synthase small subunit CarA; Belongs to the CarA family. | 0.998 |
| ACH52_0408 | carB | ACH52_0408 | ACH52_0649 | Dihydroorotase multifunctional complex type PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Carbamoyl-phosphate synthase large subunit CarB; Belongs to the CarB family. | 0.997 |
| ACH52_0408 | pyrB | ACH52_0408 | ACH52_0406 | Dihydroorotase multifunctional complex type PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Aspartate carbamoyltransferase PyrB; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| ACH52_0408 | pyrD | ACH52_0408 | ACH52_0411 | Dihydroorotase multifunctional complex type PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.999 |
| ACH52_0408 | pyrE | ACH52_0408 | ACH52_3106 | Dihydroorotase multifunctional complex type PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.958 |
| ACH52_0408 | pyrF | ACH52_0408 | ACH52_0409 | Dihydroorotase multifunctional complex type PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Orotidine 5'-phosphate decarboxylase PyrF; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.971 |
| ACH52_0410 | ACH52_0408 | ACH52_0410 | ACH52_0408 | Dihydroorotate dehydrogenase electron transfer subunit. | Dihydroorotase multifunctional complex type PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.997 |
| ACH52_0410 | ACH52_1584 | ACH52_0410 | ACH52_1584 | Dihydroorotate dehydrogenase electron transfer subunit. | Dihydropyrimidinase HydA. | 0.616 |
| ACH52_0410 | carA | ACH52_0410 | ACH52_0648 | Dihydroorotate dehydrogenase electron transfer subunit. | Carbamoyl-phosphate synthase small subunit CarA; Belongs to the CarA family. | 0.792 |
| ACH52_0410 | carB | ACH52_0410 | ACH52_0649 | Dihydroorotate dehydrogenase electron transfer subunit. | Carbamoyl-phosphate synthase large subunit CarB; Belongs to the CarB family. | 0.776 |
| ACH52_0410 | pyrB | ACH52_0410 | ACH52_0406 | Dihydroorotate dehydrogenase electron transfer subunit. | Aspartate carbamoyltransferase PyrB; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.938 |
| ACH52_0410 | pyrD | ACH52_0410 | ACH52_0411 | Dihydroorotate dehydrogenase electron transfer subunit. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.999 |
| ACH52_0410 | pyrE | ACH52_0410 | ACH52_3106 | Dihydroorotate dehydrogenase electron transfer subunit. | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.976 |
| ACH52_0410 | pyrF | ACH52_0410 | ACH52_0409 | Dihydroorotate dehydrogenase electron transfer subunit. | Orotidine 5'-phosphate decarboxylase PyrF; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.947 |
| ACH52_1584 | ACH52_0410 | ACH52_1584 | ACH52_0410 | Dihydropyrimidinase HydA. | Dihydroorotate dehydrogenase electron transfer subunit. | 0.616 |
| ACH52_1584 | ACH52_1884 | ACH52_1584 | ACH52_1884 | Dihydropyrimidinase HydA. | Sulfite reductase subunit B AsrB. | 0.616 |
| ACH52_1584 | ACH52_2235 | ACH52_1584 | ACH52_2235 | Dihydropyrimidinase HydA. | Sulfite reductase subunit B AsrB. | 0.616 |