STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnjRNA-metabolising metallo-beta-lactamase family protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (581 aa)    
Predicted Functional Partners:
rny
Ribonuclease Y Rny; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
  
 
 0.894
ybeY
rRNA maturation factor YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
 
  
 0.803
ACH52_0778
Hypothetical protein; Belongs to the UPF0473 family.
       0.778
rnr
Ribonuclease R Rnr; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
   
  
 0.731
sfsA
Sugar fermentation stimulation protein SfsA; Belongs to the SfsA family.
       0.726
ACH52_2019
FtsK/SpoIIIE family protein.
 
    0.685
pnp
Polyribonucleotide nucleotidyltransferase Pnp; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
 
  
 0.679
rpsO
Ribosomal protein S15 RpsO; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
  
  
 0.676
ACH52_0777
Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
       0.658
topA
DNA topoisomerase I TopA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA [...]
 
  
 0.653
Your Current Organism:
Eubacterium limosum
NCBI taxonomy Id: 1736
Other names: ATCC 8486, Bacteroides limosus, Butyribacterium limosum, Butyribacterium rettgeri, CCUG 16793, CIP 104169, DSM 20543, E. limosum, JCM 6421, JCM 9978, Mycobacterium limosum
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.