Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACH52_0956Xanthine/uracil permease family protein. (491 aa)    
Predicted Functional Partners:
ACH52_0897
Phosphoribosylformylglycinamidine synthase.
  
  
 0.899
purD
Phosphoribosylamine--glycine ligase PurD; Belongs to the GARS family.
  
  
 0.643
ACH52_1594
Xanthine/uracil permease family protein.
 
  
 0.639
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
  
 0.627
purM
Phosphoribosylformylglycinamidine cyclo-ligase PurM.
  
  
 0.612
ACH52_3303
Xanthine/uracil permease family protein.
 
  
 0.609
purN
Phosphoribosylglycinamide formyltransferase PurN; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
  
 0.593
purC
Phosphoribosylaminoimidazolesuccinocarboxamide synthase PurC; Belongs to the SAICAR synthetase family.
  
  
 0.587
xpt
Xanthine phosphoribosyltransferase Xpt; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
  
 0.549
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH.
  
  
 0.535
Your Current Organism:
Eubacterium limosum
NCBI taxonomy Id: 1736
Other names: ATCC 8486, Bacteroides limosus, Butyribacterium limosum, Butyribacterium rettgeri, CCUG 16793, CIP 104169, DSM 20543, E. limosum, JCM 6421, JCM 9978, Mycobacterium limosum
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