STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACH52_1027Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (152 aa)    
Predicted Functional Partners:
leuS
leucyl-tRNA synthetase LeuS; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.805
rnhB
Ribonuclease HII RnhB; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
 
 0.765
polA
DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.715
ACH52_2034
NIF3 family protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
  
  
 0.706
ACH52_1734
Phage-related single-stranded DNA-binding protein.
   
 
 0.672
ACH52_3897
Single-stranded DNA-binding protein Ssb.
   
 
 0.672
topA
DNA topoisomerase I TopA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA [...]
   
 
 0.648
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.629
ACH52_0857
Inosine-5'-monophosphate dehydrogenase GuaB.
  
  
 0.563
ACH52_1025
Amino acid racemase.
       0.509
Your Current Organism:
Eubacterium limosum
NCBI taxonomy Id: 1736
Other names: ATCC 8486, Bacteroides limosus, Butyribacterium limosum, Butyribacterium rettgeri, CCUG 16793, CIP 104169, DSM 20543, E. limosum, JCM 6421, JCM 9978, Mycobacterium limosum
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