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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACH52_1072RNA polymerase sigma factor sigma-70 family. (144 aa)    
Predicted Functional Partners:
rpoZ
DNA-directed RNA polymerase omega subunit RpoZ; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.795
rpoB
DNA-directed RNA polymerase beta subunit RpoB; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.793
rpoC
DNA-directed RNA polymerase beta' subunit RpoC; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.793
ACH52_2224
Anti-sigma regulatory factor.
  
 
 0.725
ACH52_3202
Histidine kinase.
  
 
 0.725
ACH52_3234
Anti-sigma regulatory factor.
  
 
 0.725
rpoA
DNA-directed RNA polymerase alpha subunit RpoA; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.714
ACH52_0977
Hypothetical protein.
    
 
 0.714
ACH52_3671
Recombinase/resolvase family protein.
  
     0.656
ACH52_2157
SNF2 family N-terminal domain-containing protein.
  
     0.625
Your Current Organism:
Eubacterium limosum
NCBI taxonomy Id: 1736
Other names: ATCC 8486, Bacteroides limosus, Butyribacterium limosum, Butyribacterium rettgeri, CCUG 16793, CIP 104169, DSM 20543, E. limosum, JCM 6421, JCM 9978, Mycobacterium limosum
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