Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
ACH52_1096FeFe hydrogenase H-cluster maturation GTPase HydF. (397 aa)    
Predicted Functional Partners:
ACH52_1098
FeFe hydrogenase H-cluster radical SAM maturase HydE.
   
 0.992
ACH52_1097
FeFe hydrogenase H-cluster radical SAM maturase HydG.
  
 0.976
ACH52_1099
Iron-only hydrogenase system regulator.
 
    0.920
rplA
Ribosomal protein L1 RplA; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
   
 
 0.823
ACH52_3913
Ribosomal protein L34 RpmH.
  
 
 0.808
rplB
Ribosomal protein L2 RplB; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
    
 
 0.807
rplN
Ribosomal protein L14 RplN; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
   
 
 0.805
rplS
Ribosomal protein L19 RplS; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
 
 0.803
rplM
Ribosomal protein L13 RplM; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
 
 0.802
rplX
Ribosomal protein L24 RplX; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
   
 
 0.801
Your Current Organism:
Eubacterium limosum
NCBI taxonomy Id: 1736
Other names: ATCC 8486, Bacteroides limosus, Butyribacterium limosum, Butyribacterium rettgeri, CCUG 16793, CIP 104169, DSM 20543, E. limosum, JCM 6421, JCM 9978, Mycobacterium limosum
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