node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACH52_0242 | ACH52_2610 | ACH52_0242 | ACH52_2610 | L-serine dehydratase. | L-serine dehydratase iron-sulfur-dependent beta subunit. | 0.860 |
ACH52_1467 | ACH52_1914 | ACH52_1467 | ACH52_1914 | Serine O-acetyltransferase CysE. | Threonine ammonia-lyase IlvA. | 0.823 |
ACH52_1467 | ACH52_2609 | ACH52_1467 | ACH52_2609 | Serine O-acetyltransferase CysE. | L-serine dehydratase iron-sulfur-dependent alpha subunit. | 0.908 |
ACH52_1467 | ACH52_2610 | ACH52_1467 | ACH52_2610 | Serine O-acetyltransferase CysE. | L-serine dehydratase iron-sulfur-dependent beta subunit. | 0.908 |
ACH52_1467 | ACH52_2738 | ACH52_1467 | ACH52_2738 | Serine O-acetyltransferase CysE. | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.800 |
ACH52_1467 | glyA | ACH52_1467 | ACH52_1183 | Serine O-acetyltransferase CysE. | Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.823 |
ACH52_1467 | glyA-2 | ACH52_1467 | ACH52_3167 | Serine O-acetyltransferase CysE. | Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.823 |
ACH52_1467 | glyA-3 | ACH52_1467 | ACH52_3337 | Serine O-acetyltransferase CysE. | Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.823 |
ACH52_1467 | trpA | ACH52_1467 | ACH52_2333 | Serine O-acetyltransferase CysE. | Tryptophan synthase alpha subunit TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.820 |
ACH52_1467 | trpB | ACH52_1467 | ACH52_2334 | Serine O-acetyltransferase CysE. | Tryptophan synthase beta subunit TrpB; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.818 |
ACH52_1914 | ACH52_1467 | ACH52_1914 | ACH52_1467 | Threonine ammonia-lyase IlvA. | Serine O-acetyltransferase CysE. | 0.823 |
ACH52_1914 | ACH52_2609 | ACH52_1914 | ACH52_2609 | Threonine ammonia-lyase IlvA. | L-serine dehydratase iron-sulfur-dependent alpha subunit. | 0.919 |
ACH52_1914 | ACH52_2610 | ACH52_1914 | ACH52_2610 | Threonine ammonia-lyase IlvA. | L-serine dehydratase iron-sulfur-dependent beta subunit. | 0.929 |
ACH52_1914 | ACH52_2738 | ACH52_1914 | ACH52_2738 | Threonine ammonia-lyase IlvA. | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.909 |
ACH52_1914 | glyA | ACH52_1914 | ACH52_1183 | Threonine ammonia-lyase IlvA. | Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.924 |
ACH52_1914 | glyA-2 | ACH52_1914 | ACH52_3167 | Threonine ammonia-lyase IlvA. | Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.924 |
ACH52_1914 | glyA-3 | ACH52_1914 | ACH52_3337 | Threonine ammonia-lyase IlvA. | Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.924 |
ACH52_1914 | trpA | ACH52_1914 | ACH52_2333 | Threonine ammonia-lyase IlvA. | Tryptophan synthase alpha subunit TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.924 |
ACH52_1914 | trpB | ACH52_1914 | ACH52_2334 | Threonine ammonia-lyase IlvA. | Tryptophan synthase beta subunit TrpB; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.936 |
ACH52_2609 | ACH52_1467 | ACH52_2609 | ACH52_1467 | L-serine dehydratase iron-sulfur-dependent alpha subunit. | Serine O-acetyltransferase CysE. | 0.908 |