| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACH52_0018 | ACH52_0857 | ACH52_0018 | ACH52_0857 | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | Inosine-5'-monophosphate dehydrogenase GuaB. | 0.905 |
| ACH52_0018 | ACH52_0917 | ACH52_0018 | ACH52_0917 | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.903 |
| ACH52_0018 | ACH52_2790 | ACH52_0018 | ACH52_2790 | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | 5'-nucleotidase/metallophosphoesterase domain-containing protein; Belongs to the 5'-nucleotidase family. | 0.916 |
| ACH52_0018 | ACH52_3192 | ACH52_0018 | ACH52_3192 | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | 5'-nucleotidase domain-containing protein; Belongs to the 5'-nucleotidase family. | 0.919 |
| ACH52_0018 | ACH52_3769 | ACH52_0018 | ACH52_3769 | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | Metallophosphoesterase. | 0.900 |
| ACH52_0018 | apt | ACH52_0018 | ACH52_2836 | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.900 |
| ACH52_0018 | nadD | ACH52_0018 | ACH52_2317 | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | Nicotinate (nicotinamide) nucleotide adenylyltransferase NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.903 |
| ACH52_0018 | purA | ACH52_0018 | ACH52_0647 | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | Adenylosuccinate synthase PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.905 |
| ACH52_0018 | pyrH | ACH52_0018 | ACH52_1545 | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | UMP kinase PyrH; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.900 |
| ACH52_0018 | tmk | ACH52_0018 | ACH52_3878 | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | Thymidylate kinase Tmk; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.903 |
| ACH52_0857 | ACH52_0018 | ACH52_0857 | ACH52_0018 | Inosine-5'-monophosphate dehydrogenase GuaB. | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | 0.905 |
| ACH52_0857 | ACH52_0917 | ACH52_0857 | ACH52_0917 | Inosine-5'-monophosphate dehydrogenase GuaB. | Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.862 |
| ACH52_0857 | ACH52_2790 | ACH52_0857 | ACH52_2790 | Inosine-5'-monophosphate dehydrogenase GuaB. | 5'-nucleotidase/metallophosphoesterase domain-containing protein; Belongs to the 5'-nucleotidase family. | 0.952 |
| ACH52_0857 | ACH52_3192 | ACH52_0857 | ACH52_3192 | Inosine-5'-monophosphate dehydrogenase GuaB. | 5'-nucleotidase domain-containing protein; Belongs to the 5'-nucleotidase family. | 0.928 |
| ACH52_0857 | apt | ACH52_0857 | ACH52_2836 | Inosine-5'-monophosphate dehydrogenase GuaB. | Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.457 |
| ACH52_0857 | purA | ACH52_0857 | ACH52_0647 | Inosine-5'-monophosphate dehydrogenase GuaB. | Adenylosuccinate synthase PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.989 |
| ACH52_0857 | pyrH | ACH52_0857 | ACH52_1545 | Inosine-5'-monophosphate dehydrogenase GuaB. | UMP kinase PyrH; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.538 |
| ACH52_0857 | tmk | ACH52_0857 | ACH52_3878 | Inosine-5'-monophosphate dehydrogenase GuaB. | Thymidylate kinase Tmk; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.684 |
| ACH52_0917 | ACH52_0018 | ACH52_0917 | ACH52_0018 | Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | HAD superfamily hydrolase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. | 0.903 |
| ACH52_0917 | ACH52_0857 | ACH52_0917 | ACH52_0857 | Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Inosine-5'-monophosphate dehydrogenase GuaB. | 0.862 |