Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
ACH52_3880Thioredoxin TrxA; Belongs to the thioredoxin family. (107 aa)    
Predicted Functional Partners:
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
 
 
 0.809
ACH52_2027
Ribonucleoside-diphosphate reductase adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 
 0.758
ACH52_3364
Thioredoxin-disulfide reductase TrxB.
 
 
 0.714
ACH52_3365
Thioredoxin-disulfide reductase TrxB.
 
 
 0.711
ACH52_2792
Thioredoxin-disulfide reductase TrxB.
 
 
 0.707
ACH52_3501
Pyridine nucleotide-disulfide oxidoreductase; Belongs to the sulfur carrier protein TusA family.
     
 0.649
ACH52_3710
Alkyl hydroperoxide reductase subunit F.
  
 
 0.613
ACH52_0032
Thioredoxin-disulfide reductase TrxB.
  
 
 0.565
ACH52_3879
Orn/Lys/Arg decarboxylase.
       0.552
grpE
Chaperone protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-d [...]
 
  
 0.547
Your Current Organism:
Eubacterium limosum
NCBI taxonomy Id: 1736
Other names: ATCC 8486, Bacteroides limosus, Butyribacterium limosum, Butyribacterium rettgeri, CCUG 16793, CIP 104169, DSM 20543, E. limosum, JCM 6421, JCM 9978, Mycobacterium limosum
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